| 1 | R12,2021 | Sydney Roosters v Canberra | 44-16 | W | BE | | | | |
| 2 | R14,2021 | Sydney Roosters v Gold Coast Titans | 35-34 | W | BE | | | | |
| 3 | R15,2021 | Sydney Roosters v Penrith | 12-38 | L | BE | | | | |
| 4 | R16,2021 | Sydney Roosters v Melbourne | 0-46 | L | BE | | | | |
| 5 | R17,2021 | Sydney Roosters v Canterbury | 22-16 | W | BE | | | | |
| 6 | R18,2021 | Sydney Roosters v North Queensland | 34-18 | W | BE | | | | |
| 7 | R19,2021 | Sydney Roosters v Newcastle | 28-8 | W | BE | | | | |
| 8 | R20,2021 | Sydney Roosters v Parramatta | 28-0 | W | BE | | | | |
| 9 | R21,2021 | Sydney Roosters v Penrith | 14-20 | L | BE | | | | |
| 10 | R22,2021 | Sydney Roosters v Brisbane | 21-20 | W | BE | | | | |
| 11 | R23,2021 | Sydney Roosters v St George Illawarra | 40-22 | W | BE | 1 | | | 4 |
| 12 | R24,2021 | Sydney Roosters v Souths | 12-54 | L | SR | | | | |
| 13 | R25,2021 | Sydney Roosters v Canberra | 40-16 | W | LK | | | | |
| 14 | FN,2021 | Sydney Roosters v Gold Coast Titans | 25-24 | W | BE | | | | |
| 15 | FN,2021 | Sydney Roosters v Manly | 6-42 | L | BE | | | | |